Paroxysmal nocturnal hemoglobinuria induced by the occurrence of BCR-ABL in a PIGA mutant hematopoietic progenitor cell

Leukemia. 2016 May;30(5):1208-10. doi: 10.1038/leu.2015.268. Epub 2015 Oct 6.

Authors

R Tominaga¹, T Katagiri², K Kataoka³, K Kataoka³, R K C Wee⁴, A Maeda¹, H Gomyo¹, I Mizuno¹, T Murayama¹, S Ogawa³, S Nakao⁴

Affiliations

¹ Department of Hematology, Hyogo Cancer Center, Akashi-shi, Japan.
² Clinical Laboratory Science, Division of Health Sciences, Kanazawa University Graduate School of Medical Science, Kanazawa-shi, Japan.
³ Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto-shi, Japan.
⁴ Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Kanazawa-shi, Japan.

PMID: 26437783
DOI: 10.1038/leu.2015.268

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Female
Flow Cytometry
Fusion Proteins, bcr-abl / genetics*
Hematopoietic Stem Cells / cytology
Hematopoietic Stem Cells / immunology
Hematopoietic Stem Cells / metabolism*
Hemoglobinuria, Paroxysmal / genetics*
Humans
Immunophenotyping
Membrane Proteins / genetics*
RNA, Messenger / genetics

Substances

Membrane Proteins
RNA, Messenger
phosphatidylinositol glycan-class A protein
Fusion Proteins, bcr-abl