A comprehensive Y-STR portrait of Argentinean populations

Ulises Toscanini; Carlos Vullo; Gabriela Berardi; Cintia Llull; Alicia Borosky; Andrea Gómez; Jacobo Pardo-Seco; Antonio Salas

doi:10.1016/j.fsigen.2015.09.002

A comprehensive Y-STR portrait of Argentinean populations

Forensic Sci Int Genet. 2016 Jan:20:1-5. doi: 10.1016/j.fsigen.2015.09.002. Epub 2015 Sep 8.

Authors

Ulises Toscanini¹, Carlos Vullo², Gabriela Berardi³, Cintia Llull³, Alicia Borosky², Andrea Gómez³, Jacobo Pardo-Seco⁴, Antonio Salas⁵

Affiliations

¹ PRICAI-Fundación Favaloro, Buenos Aires, Argentina; Unidade de Xenética, Departamento de Anatomía Patolóxica e Ciencias Forenses, and Instituto de Ciencias Forenses, Grupo de Medicina Xenómica (GMX), Facultade de Medicina, Universidade de Santiago de Compostela, 15872 Galicia, Spain. Electronic address: utoscanini@pricai.com.ar.
² LIDMO-EAAF, Córdoba, Argentina.
³ PRICAI-Fundación Favaloro, Buenos Aires, Argentina.
⁴ Unidade de Xenética, Departamento de Anatomía Patolóxica e Ciencias Forenses, and Instituto de Ciencias Forenses, Grupo de Medicina Xenómica (GMX), Facultade de Medicina, Universidade de Santiago de Compostela, 15872 Galicia, Spain.
⁵ Unidade de Xenética, Departamento de Anatomía Patolóxica e Ciencias Forenses, and Instituto de Ciencias Forenses, Grupo de Medicina Xenómica (GMX), Facultade de Medicina, Universidade de Santiago de Compostela, 15872 Galicia, Spain. Electronic address: antonio.salas@usc.es.

PMID: 26433179
DOI: 10.1016/j.fsigen.2015.09.002

Abstract

A study of 23 Y-STRs was conducted in 257 individuals living in urban areas from eight Argentinean provinces. The data were meta-analyzed together with 364 profiles obtained from the literature that represent other five provinces. A total of 255 different haplotypes were observed (253 singletons). Genetic structure estimated from analysis of molecular variance (AMOVA) and exploring different grouping scenarios, yielded high within population variance. Not surprisingly, analyses of genetic distances with respect to main ancestral continental populations indicated Argentinean haplotypes to be closely related to European ones. Overall, these results provide a quite complete picture of the patterns of Y chromosome variation in Argentina, notably contributing to increase the previous national database, and consequently allowing a better estimation of parameters of interest in forensic casework and parentage testing.

Keywords: Argentina; Forensic genetics; PPY23; Y-STR; YHRD.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Argentina
Chromosomes, Human, Y*
Forensic Genetics / methods
Genetics, Population
Haplotypes
Humans
Male
Microsatellite Repeats*