Oxidative stress and its impact on neurons and glia in multiple sclerosis lesions

Biochim Biophys Acta. 2016 Mar;1862(3):506-10. doi: 10.1016/j.bbadis.2015.09.018. Epub 2015 Oct 8.

Authors

Hans Lassmann¹, Jack van Horssen²

Affiliations

¹ Center for Brain Research, Medical University of Vienna, Austria. Electronic address: hans.lassmann@meduniwien.ac.at.
² Dept. of Molecular Cell Biology and Immunology, VU University Medical Center Amsterdam, Neuroscience Campus Amsterdam, The Netherlands.

PMID: 26432481
DOI: 10.1016/j.bbadis.2015.09.018

No abstract available

Keywords: Astrocytes; Microglia; Multiple sclerosis; Neurons; Oligodendrocytes; Oxidative stress.

Publication types

Review

MeSH terms

Animals
Brain / metabolism
Brain / pathology*
Humans
Iron / analysis
Iron / metabolism
Macrophages / metabolism
Macrophages / pathology
Mitochondria / metabolism
Mitochondria / pathology
Multiple Sclerosis / metabolism
Multiple Sclerosis / pathology*
Nerve Fibers, Myelinated / metabolism
Nerve Fibers, Myelinated / pathology
Neuroglia / metabolism
Neuroglia / pathology*
Neurons / metabolism
Neurons / pathology*
Oxidative Stress*

Substances

Iron