Nurse-like cells mediate ibrutinib resistance in chronic lymphocytic leukemia patients

Blood Cancer J. 2015 Oct 2;5(10):e355. doi: 10.1038/bcj.2015.74.

Authors

F Boissard^{1

2}, J-J Fournié^{1

2}, A Quillet-Mary^{1

2}, L Ysebaert^{1

2

3}, M Poupot^{1

2}

Affiliations

¹ Centre de Recherches en Cancérologie de Toulouse, INSERM UMR1037, Université Toulouse III Paul-Sabatier, ERL 5294 CNRS, Toulouse, France.
² Laboratoire d'Excellence 'TOUCAN', Programme Hospitalo-Universitaire en Cancérologie CAPTOR, Institut Carnot Lymphome CALYM, Pierre-Benite, France.
³ Institut Universitaire du Cancer de Toulouse-Oncopole, CHU de Toulouse, France.

No abstract available

Publication types

Letter

MeSH terms

Adenine / analogs & derivatives
Antineoplastic Agents / pharmacology*
Cell Differentiation / drug effects
Drug Resistance, Neoplasm / immunology*
Humans
Leukemia, Lymphocytic, Chronic, B-Cell / immunology
Leukemia, Lymphocytic, Chronic, B-Cell / pathology*
Monocytes / pathology
Piperidines
Pyrazoles / pharmacology*
Pyrimidines / pharmacology*
Tumor Microenvironment / immunology*

Substances

Antineoplastic Agents
Piperidines
Pyrazoles
Pyrimidines
ibrutinib
Adenine