Antimycoplasmic activity and seasonal variation of essential oil of Eugenia hiemalis Cambess. (Myrtaceae)

Nat Prod Res. 2016 Sep;30(17):1961-4. doi: 10.1080/14786419.2015.1091455. Epub 2015 Oct 1.

Abstract

The purpose of this work was to study the chemical composition and antimycoplasmic and anticholinesterase activities of the essential oil of Eugenia hiemalis leaves collected throughout the year. A total of 42 compounds were identified by CG, and are present in almost every seasons. Sesquiterpenes were dominant (86.01-91.48%), and non-functionalised sesquiterpenes comprised the major fraction, which increased in the summer; monoterpenes were not identified. The major components were spathulenol (5.36-16.06%), δ-cadinene (7.50-15.93%), bicyclogermacrene (5.70-14.24%) and β-caryophyllene (4.80-9.43%). The highest oil yield was obtained in summer and autumn. Essential oils presented activity against three evaluated Mycoplasma strains, but no activity was observed in the anticholinesterase assay.

Keywords: Eugenia hiemalis; Mycoplasma; antibacterial; essential oil; seasonal variation.

MeSH terms

  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / isolation & purification
  • Anti-Bacterial Agents / pharmacology
  • Eugenia / chemistry*
  • Monoterpenes / chemistry*
  • Mycoplasma / drug effects
  • Oils, Volatile / chemistry*
  • Plant Leaves / chemistry
  • Polycyclic Sesquiterpenes
  • Seasons
  • Sesquiterpenes / chemistry*

Substances

  • Anti-Bacterial Agents
  • Monoterpenes
  • Oils, Volatile
  • Polycyclic Sesquiterpenes
  • Sesquiterpenes
  • delta-cadinene
  • spathulenol
  • caryophyllene