Fulminant BCG Disease in a 7 Month Old Healthy Male Infant

J Trop Pediatr. 2015 Dec;61(6):474-7. doi: 10.1093/tropej/fmv062. Epub 2015 Sep 30.

Abstract

A seven month old healthy male infant was brought with papular skin lesions all over the body, which became ulcerative with increasing fever and redness within 1 week duration. On examination, Bacilli Calmette Guerin (BCG) scar was ulcerated with discharge; infant was irritable with tachycardia and tachypnea. Investigations revealed pancytopenia, and acid fast bacilli was positive in skin lesions and at BCG scar site. There was progressive worsening of infant's condition, culminating in death.

Keywords: BCG; disseminated; fulminant; tuberculosis..

Publication types

  • Case Reports

MeSH terms

  • BCG Vaccine / administration & dosage*
  • BCG Vaccine / adverse effects*
  • Bone and Bones / diagnostic imaging
  • Bone and Bones / pathology
  • Fatal Outcome
  • Female
  • Humans
  • Infant
  • Male
  • Mycobacterium bovis / isolation & purification*
  • Radiography
  • Skin / pathology
  • Tuberculosis / diagnosis*
  • Tuberculosis / microbiology*
  • Tuberculosis / pathology

Substances

  • BCG Vaccine