Quality of life and its determinants for heroin addicts receiving a methadone maintenance program: Comparison with matched referents from the general population

J Formos Med Assoc. 2016 Sep;115(9):714-27. doi: 10.1016/j.jfma.2015.07.007. Epub 2015 Sep 28.

Abstract

Background/purpose: Quality of life (QoL) is found to be lower in heroin addicts; however, few studies examine detailed QoL performance and related factors in heroin patients attending a methadone maintenance treatment program (MMTP). The study thus aimed to explore QoL and its determinants for publicly-funded and self-paid patients attending an MMTP.

Methods: Participants were recruited in Jianan Psychiatric Center, Tainan, Taiwan, during their first clinic visit for the MMTP. Age-, sex-, education-, and municipality-matched referents were collected from the 2001 Taiwan National Health Interview Survey database. The participants had a mean age of 38.29 years [standard deviation (SD) = 7.65 years] for publicly-funded (n = 129) and 37.97 years (SD = 7.16 years) for self-paid (n = 105) MMTP patients. Matched referents (n = 217) were 37.74 years (SD = 7.44 years). All participants were measured with the brief version of the World Health Organization's Quality of Life (WHOQOL-BREF) assessment. MMTP patients additionally went through tests for the hepatitis B virus, hepatitis C virus, and human immunodeficiency virus (HIV).

Results: Both publicly-funded and self-paid MMTP patients had lower QoL scores than their matched counterparts in the physical and psychological domains (p < 0.05) after control for confounding by age, sex, education, and municipality. Detailed individual item analyses showed that publicly-funded MMTP patients had lower scores for almost all items related to the physical, psychological, and social domains as compared to the referents because of HIV infection (p < 0.05).

Conclusion: To improve the QoL of heroin users coming for MMTP, we recommend that clinicians pay attention to the comorbidity of HIV infection and individual items/facets.

Keywords: heroin abuse; human immunodeficiency virus; methadone maintenance treatment; quality of life.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Comorbidity
  • Databases, Factual
  • Female
  • HIV Infections / complications
  • Heroin Dependence / complications
  • Heroin Dependence / drug therapy*
  • Humans
  • Male
  • Methadone / therapeutic use*
  • Middle Aged
  • Multivariate Analysis
  • Opiate Substitution Treatment*
  • Quality of Life*
  • Regression Analysis
  • Surveys and Questionnaires
  • Taiwan
  • World Health Organization

Substances

  • Methadone