Indocyanine green (ICG) fluorescence-guided laparoscopic adrenalectomy

J Surg Oncol. 2015 Nov;112(6):650-3. doi: 10.1002/jso.24057. Epub 2015 Sep 29.

Abstract

Objective: Laparoscopic adrenalectomy has become the standard of care for many adrenal tumors. However, the success of the operation hinges on identifying the adrenal vein and complete tumor resection. We demonstrate the use of a commercially available near infrared fluorescent imaging system to clearly delineate the vascular anatomy of adrenal neoplasms and enhance the border between tumor and normal tissue. We hypothesize that this will increase the safety of laparoscopic adrenalectomy.

Materials and methods: We performed laparoscopic adrenalectomy utilizing indocyanine green (ICG) and a specialized laparoscopic fluorescence imaging system on four consecutive patients undergoing laparoscopic adrenalectomy over a 4-month period.

Results: The adrenal arteries and vein were vividly enhanced with ICG fluorescence guidance, and the border between tumor and adjacent tissue was clearly demarcated. The operations were performed safely with minimal blood loss and short operative times. There were no complications.

Conclusions: Adrenal neoplasms can be resected laparoscopically under ICG fluorescence guidance and can be used to clearly identify vascular structures and enhance the borders of the tumor. This technique allows for clear identification of the adrenal vein and has the potential to improve the safety of laparoscopic adrenalectomy.

Keywords: adrenal; adrenalectomy; fluorescence-guided surgery (FGS); indocyanine green (ICG); laparoscopic.

Publication types

  • Case Reports

MeSH terms

  • Adenoma / pathology
  • Adenoma / surgery*
  • Adrenal Gland Neoplasms / pathology
  • Adrenal Gland Neoplasms / surgery*
  • Adrenalectomy*
  • Adult
  • Female
  • Fluorescent Dyes*
  • Humans
  • Indocyanine Green*
  • Laparoscopy
  • Middle Aged
  • Neoplasm Staging
  • Patient Positioning
  • Pheochromocytoma / pathology
  • Pheochromocytoma / surgery*
  • Prognosis
  • Surgery, Computer-Assisted*
  • Young Adult

Substances

  • Fluorescent Dyes
  • Indocyanine Green