Muscle strength declines with age. However, factors that contribute to such declines are not well documented and have not been extensively studied in elderly populations of Asian origin. Correlations of grip strength with a broad range of factors associated with declines in muscle strength were examined in 202 community-living elderly Japanese women. After adjustment for age, grip strength was positively correlated with body weight, height, serum albumin, haemoglobin, high-density lipoprotein cholesterol (HDL-C) and serum iron and inversely with serum copper, and log high-sensitivity C-reactive protein (hsCRP). Multiple linear regression analysis with grip strength as a dependent variable showed that 47.0% of variability of grip strength could be accounted for by height, age and haemoglobin in order of increasing R2. In conclusion, low haemoglobin may contribute to low muscle strength independently of age, anthropometric, nutritional, and inflammatory markers in the elderly, and may represent an important confounder of the association between grip strength and functional decline in community- living Japanese elderly women.
肌肉强度随年龄增长而下降。然而，导致这种下降的因素没有好的相关文献 记录和广泛研究。该研究分析了202 名社区居住的老年日本妇女握力强度相 关因素与肌肉强度下降的关系。结果表明调整了年龄的影响后，握力强度与 体重、身高、血清白蛋白、血红蛋白、高密度脂蛋白胆固醇（HDL-C）、血 清铁、血清铜的倒数、高敏C 反应蛋白（hsCRP）的对数呈正相关。多重线 性回归分析显示：以握力强度作为因变量，依据增加的吻合度，握力强度的 47%可以被身高、年龄和血红蛋白所解释。总之，在老年人群中，低血红蛋 白是独立于年龄、人体测量学、营养和炎症标志物影响低肌肉强度的因素， 对社区生活的日本老年妇女，低血红蛋白可能是握力强度和功能减退之间关 系的一个重要混杂因子。.