Nanoencapsulation for drug delivery

EXCLI J. 2014 Mar 20:13:265-86. eCollection 2014.

Abstract

Nanoencapsulation of drug/small molecules in nanocarriers (NCs) is a very promising approach for development of nanomedicine. Modern drug encapsulation methods allow efficient loading of drug molecules inside the NCs thereby reducing systemic toxicity associated with drugs. Targeting of NCs can enhance the accumulation of nanonencapsulated drug at the diseased site. This article focussed on the synthesis methods, drug loading, drug release mechanism and cellular response of nanoencapsulated drugs on liposomes, micelles, carbon nanotubes, dendrimers, and magnetic NCs. Also the uses of these various NCs have been highlighted in the field of nanotechnology.

Keywords: carbon nanotube; dendrimers; liposomes; magnetic; micelles; nanocarriers.

Publication types

  • Review