Treatment of thyroid follicular carcinoma

Abstract

Differentiated thyroid carcinoma includes 2 different tumor types, papillary (PC) and follicular carcinoma (FC), and although similar, their prognosis is different. FC is uncommon, and this has led to it often being analyzed together with PC, and therefore the true reality of this tumor is difficult to know. As a result, the diagnostic and therapeutic management and the prognostic factors in differentiated carcinoma are more predictive of PC than FC. In this review we analyze the current state of many of the therapeutic aspects of this pathology. The best surgical technique and the usefulness of associated lymphadenectomy is also analyzed. Regarding post-surgical ablation with 131I, the indications, doses and usefulness are discussed. For the remaining therapies we analyze the few indications for radiotherapy and chemotherapy, and of new drugs such as tyrosine kinase inhibitors.

Keywords: (131)I ablation; Ablación con(131)I; Ampliamente invasivo; Carcinoma folicular; Cirugía; Diferenciación; Differentiation; Follicular carcinoma; Invasion; Invasive; Invasión; Minimally invasive; Mínimamente invasivo; Surgery; Thyroid; Tiroides.