Dedicated mobile volumetric cone-beam computed tomography for human brain imaging: A phantom study

J Xray Sci Technol. 2015;23(4):473-80. doi: 10.3233/XST-150502.

Abstract

Background: Mobile computed tomography (CT) with a cone-beam source is increasingly used in the clinical field. Mobile cone-beam CT (CBCT) has great merits; however, its clinical utility for brain imaging has been limited due to problems including scan time and image quality.

Objective: The aim of this study was to develop a dedicated mobile volumetric CBCT for obtaining brain images, and to optimize the imaging protocol using a brain phantom.

Methods: The mobile volumetric CBCT system was evaluated with regards to scan time and image quality, measured as signal-to-noise-ratio (SNR), contrast-to-noise-ratio (CNR), spatial resolution (10% MTF), and effective dose. Brain images were obtained using a CT phantom.

Results: The CT scan took 5.14 s at 360 projection views. SNR and CNR were 5.67 and 14.5 at 120 kV/10 mA. SNR and CNR values showed slight improvement as the x-ray voltage and current increased (p < 0.001). Effective dose and 10% MTF were 0.92 mSv and 360 μ m at 120 kV/10 mA. Various intracranial structures were clearly visible in the brain phantom images.

Conclusions: Using this CBCT under optimal imaging acquisition conditions, it is possible to obtain human brain images with low radiation dose, reproducible image quality, and fast scan time.

Keywords: Cone-beam computed tomography; brain imaging; dedicated mobile CT; volumetric computed tomography.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Brain / diagnostic imaging*
  • Cone-Beam Computed Tomography / instrumentation*
  • Cone-Beam Computed Tomography / methods*
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Phantoms, Imaging