Integrated design of micro force sensor oriented to cell micro-operation

Technol Health Care. 2015:23 Suppl 2:S551-8. doi: 10.3233/THC-150993.

Abstract

Background: During the process of cell micro operation, the contact force between the entry needle and the cell membrane is usually a very small area to be tested.

Objective: These two features have been utilized to design a high precision micro force sensor to provide a force feedback in the process of cell micro operation.

Methods: However, PVDF (Polyvinylidene Fluoride) has continued to display both a wide range of frequency response and a highly sensitive transform between force and electricity. In this paper a charge signal is obtained. In order to transform the charge signal into a voltage signal, a signal processing circuit was designed. The data acquisition card PCI-6221 (National Instruments) was used. It was employed to collect the voltage signal.

Results: The resultant micro force sensor was calibrated by using a rating test.

Conclusions: The experimental test results demonstrated that the sensitivity and linearity of the designed micro force sensor were higher than the sensitivity and linearity of a traditional piezoelectric sensor.

Keywords: Cell micro-operation; PVDF; charge amplifier; micro force sensor.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Membrane*
  • Electricity*
  • Equipment Design
  • Genetic Engineering / methods*
  • Humans
  • Mechanical Phenomena
  • Needles*
  • Polyvinyls / chemistry*

Substances

  • Polyvinyls
  • polyvinylidene fluoride