Contrast-associated Acute Kidney Injury

Crit Care Clin. 2015 Oct;31(4):725-35. doi: 10.1016/j.ccc.2015.06.008. Epub 2015 Jul 29.

Abstract

Contrast-associated acute kidney injury (CAAKI) is a common iatrogenic condition. The principal risk factors for CAAKI are underlying renal impairment; diabetes in the setting of kidney disease; and intravascular volume depletion, effective or absolute. CAAKI is associated with serious adverse short-term and long-term outcomes, including mortality and more rapidly progressive chronic kidney disease, although the causal nature of these associations remains unproved. Patients with chronic kidney disease and other risk factors for CAAKI who present with acute coronary syndrome should undergo indicated angiographic procedures.

Keywords: Acute kidney injury; Contrast; Iatrogenic; Nephrotoxin; Prevention.

Publication types

  • Review

MeSH terms

  • Acute Kidney Injury / chemically induced*
  • Acute Kidney Injury / epidemiology
  • Acute Kidney Injury / prevention & control*
  • Contrast Media / administration & dosage
  • Contrast Media / adverse effects*
  • Diuretics / therapeutic use
  • Fluid Therapy
  • Humans
  • Renal Replacement Therapy
  • Risk Assessment
  • Risk Factors

Substances

  • Contrast Media
  • Diuretics