Classification of semi-automated flare readings using the Kowa FM 700 laser cell flare meter in patients with uveitis

Acta Ophthalmol. 2016 Mar;94(2):e135-41. doi: 10.1111/aos.12833. Epub 2015 Sep 26.

Abstract

Purpose: To propose a classification system to grade semi-automated flare readings and assess its correlation with clinical flare grading and also to explore the utility of an additional step in clinical flare assessment between grades 0 and 1.

Methods: Semi-automated flare readings from 103 eyes with uveitis were taken using the Kowa FM 700 laser flare meter and classified into two models (LFCM and LFCM_1), and introduction of a 0.5 step in flare grading was explored.

Results: Good correlation was present between the conventional SUN clinical flare and the proposed clinical classification for flare (weighted kappa (WK) = 89.64%, p < 0.001). Semi-automated flare grading (LFCM and LFCM_1) had WK agreement of 82.52% and 79.85% (p < 0.001) with conventional SUN clinical flare grading.

Conclusions: The proposed classification system for semi-automated laser flare readings (LFCM) allows stratification of measurements into grades analogous to clinical flare grades and correlates well with conventional clinical flare grading.

Keywords: anterior chamber flare; anterior chamber reaction; grading of ocular inflammation; laser flare meter; ocular inflammation; semi-automated laser flare.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anterior Chamber / pathology*
  • Diagnostic Techniques, Ophthalmological / classification*
  • Diagnostic Techniques, Ophthalmological / instrumentation
  • Female
  • Humans
  • Male
  • Middle Aged
  • Photometry / classification*
  • Photometry / instrumentation
  • Retrospective Studies
  • Uveitis, Anterior / classification*
  • Uveitis, Anterior / diagnosis*
  • Young Adult