Lateral resolution enhancement using programmable phase modulator in optical coherence tomography

Biomed Mater Eng. 2015:26 Suppl 1:S1465-71. doi: 10.3233/BME-151445.

Abstract

Adaptive optics plays an important role in the correction of high-order aberrations to enhance lateral resolution. An OCT system coupled with a programmable phase modulator is designed to verify lateral resolution improvement. The Hamamatsu high-resolution, non-pixelized, optically addressed light modulator (PAL-SLM) PPM X7550 series is used to correct aberrations, utilizing a simple method based on phase information from OCT images. The advantages of this method are its high simplicity and low cost. A raster scanning technique is adopted to scan samples covered with scattering suspension. Metal lines covered with scattering suspension are imaged, and a respective correction is applied to remove the aberration. Results demonstrate an improvement in lateral resolution on metal grid samples.

Keywords: OCT; PAL-SLM; aberration correction; adaptive optics; lateral resolution.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Equipment Design
  • Equipment Failure Analysis
  • Image Enhancement / instrumentation*
  • Image Interpretation, Computer-Assisted / instrumentation*
  • Optical Devices*
  • Phantoms, Imaging
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Signal Processing, Computer-Assisted / instrumentation*
  • Tomography, Optical Coherence / instrumentation*