High-resolution fluorodeoxyglucose positron emission tomography and magnetic resonance imaging findings of a pituitary microtumor in a dog

Young-Don Son; Da-Jung Kim; Ji-Houn Kang; Dong-Woo Chang; Young-Bae Jin; Dong-In Jung; Chulhyun Lee; Mhan-Pyo Yang; Sang-Rae Lee; Byeong-Teck Kang

doi:10.1186/s13620-015-0050-5

High-resolution fluorodeoxyglucose positron emission tomography and magnetic resonance imaging findings of a pituitary microtumor in a dog

Ir Vet J. 2015 Sep 23;68(1):22. doi: 10.1186/s13620-015-0050-5. eCollection 2015.

Authors

Young-Don Son^#^{1

2}, Da-Jung Kim^#³, Ji-Houn Kang⁴, Dong-Woo Chang⁵, Young-Bae Jin⁶, Dong-In Jung⁷, Chulhyun Lee⁸, Mhan-Pyo Yang⁴, Sang-Rae Lee⁶, Byeong-Teck Kang³

Affiliations

¹ Neuroscience Research Institute, Gachon University, Incheon, South Korea.
² Department of Biomedical Engineering, College of Health Science, Gachon University, Incheon, South Korea.
³ Laboratory of Veterinary Dermatology and Neurology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk South Korea.
⁴ Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk South Korea.
⁵ Laboratory of Veterinary Radiology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk South Korea.
⁶ The National Primate Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Ochang, Chungbuk Republic of Korea.
⁷ Institute of Animal Medicine, Gyeongsang National University, Jinju, South Korea.
⁸ Center of Magnetic Resonance Research, Korea Basic Science Institute, Ochang, Chungbuk Republic of Korea.

^# Contributed equally.

Abstract

A 16-year-old, castrated, male English cocker spaniel dog was presented due to generalized alopecia. Routine clinical pathology, endocrine and abdominal ultrasonography results were consistent with a diagnosis of pituitary-dependent hyperadrenocorticism. The adenohypophyseal lesion was clearly visualized on both 3 T and 7 T magnetic resonance imaging (MRI) of the pituitary gland. Although biochemical and MRI findings were consistent with a functional pituitary microtumor, a pituitary lesion was not detected using (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET). This report firstly describes the application of high-resolution FDG-PET to a spontaneous pituitary microtumor in a dog.

Keywords: Dog; Fluorodeoxyglucose positron emission tomography; Magnetic resonance imaging; Pituitary microtumor.