A two-pronged attack against mantle cell lymphoma

Blood. 2015 Sep 24;126(13):1521-3. doi: 10.1182/blood-2015-08-662106.

Abstract

In this issue of Blood, Bhatt et al describe direct cytotoxic and indirect immune cell-mediated effects of interleukin-21 (IL-21) in mantle cell lymphoma (MCL), providing a preclinical rationale for IL-21 therapy in this aggressive disease.

Publication types

  • Comment

MeSH terms

  • Animals
  • Female
  • Humans
  • Immunologic Factors / immunology*
  • Immunologic Factors / therapeutic use*
  • Interleukins / immunology*
  • Interleukins / therapeutic use*
  • Lymphoma, Mantle-Cell / immunology*
  • Lymphoma, Mantle-Cell / therapy*

Substances

  • Immunologic Factors
  • Interleukins