Emergence of ONPG-negative Shigella sonnei in Shanghai, China

Diagn Microbiol Infect Dis. 2015 Dec;83(4):338-40. doi: 10.1016/j.diagmicrobio.2015.08.010. Epub 2015 Aug 20.

Abstract

Shigella sonnei has become predominant species causing shigellosis in Shanghai. Two hundred ninety-three S. sonnei were isolated in sentinel hospitals of Shanghai in 2011. We found an emergence of 8 strains of S. sonnei with negative phenotype for o-nitrophenyl-β-d-galactopyranoside in late August, which showed distinct pulsed-field gel electrophoresis patterns from the other 285 S. sonnei and had genes deletion in lac and mhp operons.

Keywords: Emergence; Gene deletion; ONPG-negative; Phenotype; Shigella sonnei.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Bacterial Typing Techniques
  • China
  • Dysentery, Bacillary / microbiology*
  • Electrophoresis, Gel, Pulsed-Field
  • Female
  • Gene Deletion
  • Genotype
  • Hospitals
  • Humans
  • Male
  • Middle Aged
  • Molecular Typing
  • Nitrophenylgalactosides / metabolism*
  • Phenotype
  • Shigella sonnei / classification*
  • Shigella sonnei / genetics
  • Shigella sonnei / isolation & purification*
  • Shigella sonnei / metabolism
  • Young Adult

Substances

  • 2-nitrophenylgalactoside
  • Nitrophenylgalactosides