Recent Progress in Fluorescent Imaging Probes

Sensors (Basel). 2015 Sep 22;15(9):24374-96. doi: 10.3390/s150924374.

Abstract

Due to the simplicity and low detection limit, especially the bioimaging ability for cells, fluorescence probes serve as unique detection methods. With the aid of molecular recognition and specific organic reactions, research on fluorescent imaging probes has blossomed during the last decade. Especially, reaction based fluorescent probes have been proven to be highly selective for specific analytes. This review highlights our recent progress on fluorescent imaging probes for biologically important species, such as biothiols, reactive oxygen species, reactive nitrogen species, metal ions including Zn(2+), Hg(2+), Cu(2+) and Au(3+), and anions including cyanide and adenosine triphosphate (ATP).

Keywords: fluorescent chemosensors; fluorescent chemosensors for ROS; fluorescent chemosensors for biothiols; fluorescent chemosensors for metal ions; fluorescent probes; imaging probes.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Fluorescent Dyes / chemistry*
  • Humans
  • Hydrogen Peroxide / chemistry
  • Metals / chemistry
  • Molecular Imaging / methods*
  • Sulfhydryl Compounds / chemistry

Substances

  • Fluorescent Dyes
  • Metals
  • Sulfhydryl Compounds
  • Hydrogen Peroxide