A Review of Patterned Organic Bioelectronic Materials and their Biomedical Applications

Adv Mater. 2015 Dec 9;27(46):7583-619. doi: 10.1002/adma.201501809. Epub 2015 Sep 23.

Abstract

Organic electronic materials are rapidly emerging as superior replacements for a number of conventional electronic materials, such as metals and semiconductors. Conducting polymers, carbon nanotubes, graphenes, organic light-emitting diodes, and diamond films fabricated via chemical vapor deposition are the most popular organic bioelectronic materials that are currently under active research and development. Besides the capability to translate biological signals to electrical signals or vice versa, organic bioelectronic materials entail greater biocompatibility and biodegradability compared to conventional electronic materials, which makes them more suitable for biomedical applications. When patterned, these materials bring about numerous capabilities to perform various tasks in a more-sophisticated and high-throughput manner. Here, we provide an overview of the unique properties of organic bioelectronic materials, different strategies applied to pattern these materials, and finally their applications in the field of biomedical engineering, particularly biosensing, cell and tissue engineering, actuators, and drug delivery.

Keywords: biosensing; carbon nanotubes; cell and tissue engineering; conductive polymers; drug delivery.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials / chemistry*
  • Biosensing Techniques / instrumentation
  • Biosensing Techniques / methods
  • Drug Carriers / chemistry
  • Electronics*
  • Graphite / chemistry
  • Nanotubes, Carbon / chemistry
  • Polymers / chemistry
  • Semiconductors
  • Tissue Engineering

Substances

  • Biocompatible Materials
  • Drug Carriers
  • Nanotubes, Carbon
  • Polymers
  • Graphite