Imaging of Fluid in Cancer Patients Treated With Systemic Therapy: Chemotherapy, Molecular Targeted Therapy, and Hematopoietic Stem Cell Transplantation

Abhishek R Keraliya; Michael H Rosenthal; Katherine M Krajewski; Jyothi P Jagannathan; Atul B Shinagare; Sree Harsha Tirumani; Nikhil H Ramaiya

doi:10.2214/AJR.15.14459

Imaging of Fluid in Cancer Patients Treated With Systemic Therapy: Chemotherapy, Molecular Targeted Therapy, and Hematopoietic Stem Cell Transplantation

AJR Am J Roentgenol. 2015 Oct;205(4):709-19. doi: 10.2214/AJR.15.14459.

Authors

Abhishek R Keraliya^{1

2}, Michael H Rosenthal^{1

2}, Katherine M Krajewski^{1

2}, Jyothi P Jagannathan^{1

2}, Atul B Shinagare^{1

2}, Sree Harsha Tirumani^{1

2}, Nikhil H Ramaiya^{1

2}

Affiliations

¹ 1 All authors: Department of Imaging, Dana Farber Cancer Institute, Harvard Medical School, 450 Brookline Ave, Boston, MA 02215.
² 2 All authors: Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

PMID: 26397319
DOI: 10.2214/AJR.15.14459

Abstract

Objective: The purpose of this article is to provide a comprehensive review of the imaging features of various systemic treatment-related causes of fluid accumulation in cancer patients.

Conclusion: Systemic treatment-related fluid accumulation can occur with chemotherapy, molecular targeted therapy, or hematopoietic stem cell transplantation. Imaging findings such as new ascites, pleural and pericardial effusions, and subcutaneous edema should be interpreted with caution on restaging studies.

Keywords: fluid; hematopoietic stem cell transplantation; molecular targeted therapy.

Publication types

Review

MeSH terms

Antineoplastic Agents / adverse effects*
Ascites / diagnosis
Ascites / etiology
Diagnostic Imaging*
Edema / diagnosis*
Edema / etiology
Hematopoietic Stem Cell Transplantation / adverse effects*
Humans
Molecular Targeted Therapy / adverse effects*
Neoplasms / complications
Neoplasms / diagnosis
Neoplasms / therapy*
Pericardial Effusion / diagnosis
Pericardial Effusion / etiology
Pleural Effusion / diagnosis
Pleural Effusion / etiology

Substances

Antineoplastic Agents