Ammonia Levels Should Not Be Used as a Surrogate Marker of Levels of Asparaginase Activity in Acute Lymphoblastic Leukemia Patients

Pediatr Blood Cancer. 2016 Mar;63(3):564-5. doi: 10.1002/pbc.25767. Epub 2015 Sep 23.

Authors

Wing H Tong¹, Rob Pieters^{1

2}, Inge M van der Sluis¹

Affiliations

¹ Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.
² Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.

PMID: 26397054
DOI: 10.1002/pbc.25767

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Ammonia / blood*
Asparaginase / blood*
Asparaginase / therapeutic use
Biomarkers / blood*
Child
Humans
Precursor Cell Lymphoblastic Leukemia-Lymphoma / blood*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
Prospective Studies

Substances

Biomarkers
Ammonia
Asparaginase