Crystal structure of 3-amino-2-ethyl-quinazolin-4(3H)-one

Gamal A El-Hiti; Keith Smith; Amany S Hegazy; Mohammed Baashen; Benson M Kariuki

doi:10.1107/S2056989015014450

Crystal structure of 3-amino-2-ethyl-quinazolin-4(3H)-one

Acta Crystallogr E Crystallogr Commun. 2015 Aug 6;71(Pt 9):o650-1. doi: 10.1107/S2056989015014450. eCollection 2015 Sep 1.

Authors

Gamal A El-Hiti¹, Keith Smith², Amany S Hegazy², Mohammed Baashen³, Benson M Kariuki²

Affiliations

¹ Cornea Research Chair, Department of Optometry, College of Applied Medical Sciences, King Saud University, PO Box 10219, Riyadh 11433, Saudi Arabia.
² School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, Wales.
³ Department of Chemistry, Faculty of Science and Humanities, Shaqra University, Al-Duwadmi, Saudi Arabia.

Abstract

The mol-ecule of the title compound, C10H11N3O, is planar, including the ethyl group, as indicated by the N-C-C-C torsion angle of 1.5 (2)°. In the crystal, inversion-related mol-ecules are stacked along the a axis. Mol-ecules are oriented head-to-tail and display π-π inter-actions with a centroid-to-centroid distance of 3.6664 (8) Å. N-H⋯O hydrogen bonds between mol-ecules generate a 'step' structure through formation of an R 2 (2)(10) ring.

Keywords: 3-amino-2-ethylquinazolin-4(3H)-one; crystal structure; π–π interactions.