Iron-promoted C-C bond formation in the total synthesis of natural products and drugs

Nat Prod Rep. 2015 Nov;32(11):1541-55. doi: 10.1039/c5np00059a. Epub 2015 Sep 23.

Abstract

Iron salts are inexpensive and almost innocuous; they are thus the promoters of choice, even in stoichiometric amounts, for the formation of carbon-carbon bonds in the backbone of complex molecules. This review encompasses the key role of iron complexes in the total synthesis of some natural products or pharmacologically important compounds.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biological Products / chemical synthesis*
  • Biological Products / chemistry
  • Carbon / chemistry*
  • Iron / chemistry*
  • Molecular Structure
  • Pharmaceutical Preparations / chemical synthesis*
  • Pharmaceutical Preparations / chemistry

Substances

  • Biological Products
  • Pharmaceutical Preparations
  • Carbon
  • Iron