Energy Migration Engineering of Bright Rare-Earth Upconversion Nanoparticles for Excitation by Light-Emitting Diodes

Adv Mater. 2015 Nov 4;27(41):6418-22. doi: 10.1002/adma.201502272. Epub 2015 Sep 22.

Abstract

A novel Nd(3+) -sensitized upconversion nanoparticle (UCNP) that can be excited by near-infrared 740 nm light-emitting diode (LED) lamps with bright upconversion luminescence is designed. Yb(3+) ion distribution is engineered to increase the energy migration efficiency. The benefit of the novel LED-excited UCNPs is demonstrated by imaging of breast cancer cells and enabling an economic handheld semiquantitative visual measurement device.

Keywords: energy migration; light-emitting diodes; upconversion, nanoparticles.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line, Tumor
  • Energy Transfer
  • Fluorides / chemistry
  • HEK293 Cells
  • HeLa Cells
  • Humans
  • Infrared Rays
  • Metals, Rare Earth / chemistry*
  • Microscopy, Fluorescence
  • Nanoparticles / chemistry*
  • Peptides / chemistry
  • Peptides / metabolism
  • Receptor, ErbB-2 / metabolism
  • Ytterbium / chemistry
  • Yttrium / chemistry

Substances

  • Metals, Rare Earth
  • Peptides
  • sodium yttriumtetrafluoride
  • Yttrium
  • ERBB2 protein, human
  • Receptor, ErbB-2
  • Ytterbium
  • Fluorides