IgG4-related stomach muscle lesion with a renal pseudotumor and multiple renal rim-like lesions: A rare manifestation of IgG4-related disease

Koichi Inoue; Takehiko Okubo; Takashi Kato; Kazuo Shimamura; Teruji Sugita; Mitsuhiro Kubota; Kohji Kanaya; Daisuke Yamachika; Makoto Sato; Dai Inoue; Kenichi Harada; Mitsuhiro Kawano

doi:10.3109/14397595.2015.1081743

IgG4-related stomach muscle lesion with a renal pseudotumor and multiple renal rim-like lesions: A rare manifestation of IgG4-related disease

Mod Rheumatol. 2018 Jan;28(1):188-192. doi: 10.3109/14397595.2015.1081743. Epub 2015 Sep 18.

Authors

Affiliations

¹ a Division of Surgery , Yamachika Memorial Hospital, Odawara, Kanagawa , Japan.
² b Division of Internal Medicine , Yamachika Memorial Hospital, Odawara, Kanagawa , Japan.
³ c Division of Rheumatology , Yamachika Memorial Hospital, Odawara, Kanagawa , Japan.
⁴ d Division of Pathology , Yamachika Memorial Hospital, Odawara, Kanagawa , Japan.
⁵ e Department of Radiology , Kanazawa University Graduate School of Medicine , Kanazawa , Ishikawa , Japan.
⁶ f Department of Human Pathology , Kanazawa University Graduate School of Medicine , Kanazawa , Ishikawa , Japan , and.
⁷ g Division of Rheumatology, Department of Internal Medicine , Kanazawa University Graduate School of Medicine , Kanazawa , Ishikawa , Japan.

PMID: 26381653
DOI: 10.3109/14397595.2015.1081743

Abstract

We describe a 74-year-old man with immunoglobulin G4-related disease (IgG4-RD) presenting with gastric cancer, stomach and kidney lesions. For 15 years, the patient had been treated under a diagnosis of sclerosing cholangitis, which was revealed to be IgG4-RD only when the cancer was found. Histology revealed the gastric cancer and IgG4-related lesion in the muscularis propria to be separate. This case suggests that the stomach muscle can also be a site of involvement of IgG4-RD.

Keywords: Gastric cancer; IgG4-related disease; IgG4-related kidney disease; muscularis propria.

Publication types

Case Reports

MeSH terms

Aged
Autoimmune Diseases / blood
Autoimmune Diseases / complications*
Humans
Immunoglobulin G / blood*
Immunologic Tests
Kidney Diseases / blood
Kidney Diseases / etiology*
Male
Stomach Neoplasms / blood
Stomach Neoplasms / etiology*

Substances

Immunoglobulin G