How can novel microscopic approaches shed light on the function of nucleic acid-based drugs?

Future Med Chem. 2015;7(13):1623-5. doi: 10.4155/fmc.15.110. Epub 2015 Sep 18.
No abstract available

Keywords: Cryo-EM; EDS; FRET; RNAi; TEM; TIRF; confocal; siRNA; super-resolution.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Drug Discovery / methods*
  • Fluorescence Resonance Energy Transfer / methods
  • Humans
  • Microscopy, Electron, Transmission / methods*
  • Microscopy, Fluorescence / methods*
  • Nucleic Acids / administration & dosage
  • Nucleic Acids / pharmacokinetics*
  • Nucleic Acids / pharmacology*

Substances

  • Nucleic Acids