Ochratoxin A Dietary Exposure of Ten Population Groups in the Czech Republic: Comparison with Data over the World

Toxins (Basel). 2015 Sep 10;7(9):3608-35. doi: 10.3390/toxins7093608.

Abstract

Ochratoxin A is a nephrotoxic and renal carcinogenic mycotoxin and is a common contaminant of various food commodities. Eighty six kinds of foodstuffs (1032 food samples) were collected in 2011-2013. High-performance liquid chromatography with fluorescence detection was used for ochratoxin A determination. Limit of quantification of the method varied between 0.01-0.2 μg/kg depending on the food matrices. The most exposed population is children aged 4-6 years old. Globally for this group, the maximum ochratoxin A dietary exposure for "average consumer" was estimated at 3.3 ng/kg bw/day (lower bound, considering the analytical values below the limit of quantification as 0) and 3.9 ng/kg bw/day (middle bound, considering the analytical values below the limit of quantification as 1/2 limit of quantification). Important sources of exposure for this latter group include grain-based products, confectionery, meat products and fruit juice. The dietary intake for "high consumers" in the group 4-6 years old was estimated from grains and grain-based products at 19.8 ng/kg bw/day (middle bound), from tea at 12.0 ng/kg bw/day (middle bound) and from confectionery at 6.5 ng/kg bw/day (middle bound). For men aged 18-59 years old beer was the main contributor with an intake of 2.60 ng/kg bw/day ("high consumers", middle bound). Tea and grain-based products were identified to be the main contributors for dietary exposure in women aged 18-59 years old. Coffee and wine were identified as a higher contributor of the OTA intake in the population group of women aged 18-59 years old compared to the other population groups.

Keywords: Czech population; dietary exposure; exposure sources; food; ochratoxin A.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Beer / microbiology
  • Child
  • Child, Preschool
  • Coffee / microbiology
  • Czech Republic
  • Edible Grain / microbiology
  • Female
  • Food Contamination / analysis*
  • Food Microbiology
  • Fruit and Vegetable Juices / microbiology
  • Humans
  • Male
  • Meat Products
  • Middle Aged
  • Ochratoxins / administration & dosage
  • Ochratoxins / analysis*
  • Ochratoxins / toxicity
  • Population Groups*
  • Wine / microbiology
  • Young Adult

Substances

  • Coffee
  • Ochratoxins
  • ochratoxin A