The effect of vitamin D auxiliary rehabilitation therapy in children with cerebral palsy and language dysfunction

Minerva Pediatr. 2019 Dec;71(6):495-499. doi: 10.23736/S0026-4946.17.04375-4. Epub 2015 Sep 11.

Abstract

Background: The aim of the present study was to observe the clinical efficacy of vitamin D auxiliary rehabilitation therapy in children with cerebral palsy and language dysfunction.

Methods: Eighty-two cases of children with cerebral palsy and language dysfunction in our hospital from March 2011 to June 2014 were selected for this study. They were divided into two groups: the rehabilitation treatment group (simple group, N.=39) and the vitamin D auxiliary rehabilitation therapy group (combination group, N.=43). After three months of treatment, language development, Gesell Child Development Scale, Bayley Infant Development Scale score and vitamin D and calcium levels were compared.

Results: The language development, Gesell Child Development Scale, Bayley Infant Development Scale score and vitamin D and calcium levels for two of the groups, after treatment, are improved compared to before treatment. The difference was statistically significant (P<0.05). The total efficiency of the language development in the combination group was obviously higher than the simple group. The difference was significant (95.3% vs. 74.4%, χ2=2.486, P=0.032). The Gesell Child Development Scale improved in the combination group compared to the simple group. The difference was statistically significant (70.4±11.3 vs. 53.3±10.5, t=3.127, P=0.026). The proportion of normal children was significantly higher than the rehabilitation treatment group, and the difference was statistically significant (30.2% vs. 20.5%, χ2=3.016, P=0.029). In the combination group, the vitamin D and calcium levels were statistically increased compared to the rehabilitation treatment group. It had statistical differences between the two groups (P<0.05).

Conclusions: Vitamin D auxiliary rehabilitation therapy could improve the language function and the language development status in children with cerebral palsy and language dysfunction.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Calcium / blood*
  • Cerebral Palsy / rehabilitation*
  • Child, Preschool
  • Combined Modality Therapy
  • Female
  • Humans
  • Infant
  • Language Disorders / rehabilitation*
  • Male
  • Treatment Outcome
  • Vitamin D / administration & dosage*
  • Vitamin D / blood

Substances

  • Vitamin D
  • Calcium