Effects of flavonol-rich green tea cultivar (Camellia sinensis L.) on plasma oxidized LDL levels in hypercholesterolemic mice

Biosci Biotechnol Biochem. 2016;80(2):360-2. doi: 10.1080/09168451.2015.1083400. Epub 2015 Sep 12.

Abstract

To examine the possible benefits of tea flavonols, we compared anti-atherogenic effects between common and flavonol-rich tea cultivars. The tea infusion made from a flavonol-rich cultivar, but not a common cultivar, significantly decreased the plasma oxidized low-density lipoprotein level in mice fed a high-cholesterol diet. The result suggests that tea flavonols have the potential to protect against cardiovascular diseases.

Keywords: flavonol glycosides; green tea cultivars; hypercholesterolemic mice; plasma oxidized LDL.

MeSH terms

  • Animals
  • Camellia sinensis / chemistry*
  • Cholesterol, Dietary / adverse effects*
  • Diet, High-Fat*
  • Flavonols / pharmacology*
  • Hypercholesterolemia / blood
  • Hypercholesterolemia / diet therapy*
  • Hypercholesterolemia / etiology
  • Hypercholesterolemia / pathology
  • Lipoproteins, LDL / blood
  • Male
  • Mice
  • Mice, Inbred ICR
  • Tea / chemistry*

Substances

  • Cholesterol, Dietary
  • Flavonols
  • Lipoproteins, LDL
  • Tea
  • oxidized low density lipoprotein