Nematicidal triterpenoids from Lantana camara

Chem Biodivers. 2015 Sep;12(9):1435-42. doi: 10.1002/cbdv.201400460.

Abstract

A new triterpene, lancamarolide (1), and seven known triterpenes, oleanonic acid (2), lantadene A (3), 11α-hydroxy-3-oxours-12-en-28-oic acid (4), betulinic acid (5), lantadene B (6), and lantaninilic acid (7) were isolated from the aerial parts of Lantana camara in the course of bioassay-guided isolation, and their nematicidal activities against Meloidogyne incognita, the root knot nematode, were carried out. Oleanonic acid was found to be the most active compound and exhibited 80% mortality after 72 h at 0.0625% concentration, which is comparable with that of the standard furadan.

Keywords: Lancamarolide; Lantana camara; Meloidogyne incognita; Nematicidal activity; Root-knot nematodes; Triterpenoids.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antinematodal Agents / chemistry*
  • Antinematodal Agents / isolation & purification
  • Antinematodal Agents / pharmacology*
  • Humans
  • Lantana / chemistry*
  • Plants / parasitology*
  • Secernentea Infections / drug therapy
  • Triterpenes / chemistry*
  • Triterpenes / isolation & purification
  • Triterpenes / pharmacology*
  • Tylenchoidea / drug effects*

Substances

  • Antinematodal Agents
  • Triterpenes
  • oleanonic acid