Survey About the Cancer Risk of Renal Transplant Recipients

Transplant Proc. 2015 Sep;47(7):2196-7. doi: 10.1016/j.transproceed.2015.07.025.

Abstract

Introduction: There is a greater risk of malignant tumors developing in kidney transplant patients. Due to this, early detection is of outmost importance, in which screening tests play an important role.

Methods: We have conducted a survey among renal transplant recipients to assess individual risk factors.

Results: Of 530 respondents, 55 developed post-transplantation tumors. Cutaneous tumors (36%) and kidney cancer (16%) were the most frequent. In total, 59% of recipients were over the age of 50, 61.7% were over the normal body-mass index range, 40.3% smoked or used to smoke, and 21.8% had diabetes. Five patients had hepatitis B virus and 11 were hepatitis C virus-positive. Malignancies developed significantly more frequent in men than in women (P = .04). The progressing of age (P = .0001) and the time elapsed after transplantation (P < .01) also were associated with a significant increase in the occurrence of post-transplantation tumors.

Conclusion: We have created a database to facilitate a more personalized and efficient screening program for immunocompromised patients.

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Body Mass Index
  • Early Detection of Cancer / methods
  • Female
  • Humans
  • Immunocompromised Host*
  • Incidence
  • Kidney Transplantation / adverse effects*
  • Male
  • Middle Aged
  • Neoplasms / diagnosis
  • Neoplasms / epidemiology
  • Neoplasms / etiology*
  • Risk Assessment / methods*
  • Smoking / adverse effects
  • Surveys and Questionnaires
  • Time Factors