Value of screening endoscopy in evaluation of esophageal, gastric and colon cancers

World J Gastroenterol. 2015 Sep 7;21(33):9693-706. doi: 10.3748/wjg.v21.i33.9693.

Abstract

Esophageal, gastric, and colorectal cancers are deadly diseases that continue to plague our world today. The value of screening endoscopy in evaluating these types of cancers is a critical area of discussion due to a potential reduction in morbidity and mortality. This article describes how to identify a good screening test and explains what are important criteria in the field of screening endoscopy. Furthermore, the current status and progress of screening endoscopy for esophageal, gastric, and colorectal cancer will be evaluated and discussed. Mass screening programs have not been implemented for esophageal and gastric carcinomas in those with average or low risk populations. However, studies of high-risk populations have found value and a cost-benefit in conducting screening endoscopy. Colorectal cancer, on the other hand, has had mass screening programs in place for many years due to the clear evidence of improved outcomes. As the role of endoscopy as a screening tool has continued to develop, newer technology and techniques have emerged to improve its utility. Many new image enhancement techniques and computer processing programs have shown promise and may have a significant role in the future of endoscopic screening. These developments are paving the way for improving the diagnostic and therapeutic capability of endoscopy in the field of gastroenterology.

Keywords: Colon cancer; Endoscopic screening; Esophageal cancer; Esophagogastroduodenoscopy; Gastric cancer.

Publication types

  • Review

MeSH terms

  • Colonic Neoplasms / economics
  • Colonic Neoplasms / epidemiology
  • Colonic Neoplasms / pathology*
  • Cost-Benefit Analysis
  • Early Detection of Cancer / economics
  • Early Detection of Cancer / methods*
  • Endoscopy, Gastrointestinal* / economics
  • Esophageal Neoplasms / economics
  • Esophageal Neoplasms / epidemiology
  • Esophageal Neoplasms / pathology*
  • Health Care Costs
  • Humans
  • Predictive Value of Tests
  • Prognosis
  • Risk Factors
  • Stomach Neoplasms / economics
  • Stomach Neoplasms / epidemiology
  • Stomach Neoplasms / pathology*