Oncoplastic reduction mammoplasty for breast cancer in women with macromastia: Oncological long-term outcomes

Asian J Surg. 2017 Jan;40(1):41-47. doi: 10.1016/j.asjsur.2015.07.007. Epub 2015 Sep 8.

Abstract

Objective: To evaluate the long-term results of tumorectomy and concomitant bilateral oncoplastic reduction mammoplasty (ORM) for early stage breast cancer patients with macromastia in terms of local disease control and long-term oncological results.

Patients and method: Data of 82 patients with macromastia undergoing ORM for breast cancer between 1996 and 2011 were retrospectively examined and evaluated with regard to oncological results.

Results: The median age was 50 years. The median follow-up was 121 months (range 28-212 months). The median breast volume was 1402 cm3 and the median weight of excised breast material was 679 g. The median surgical margin was 16 mm. Ten-year local recurrence rate was 8.7%. The 10-year overall survival rate was 82.2% and the disease-free survival rate was 73.2%. Early and late complication rates were 12.2% and 14.6%, respectively.

Conclusions: From the standpoint of local disease control and long-term observation, ORM can be considered a very safe and acceptable treatment for early stage breast cancer in women with macromastia.

Keywords: breast cancer; cosmesis; macromastia; oncoplastic breast reduction; satisfaction.

MeSH terms

  • Adult
  • Aged
  • Breast / abnormalities*
  • Breast / surgery
  • Breast Neoplasms / complications
  • Breast Neoplasms / mortality
  • Breast Neoplasms / surgery*
  • Carcinoma, Ductal, Breast / complications
  • Carcinoma, Ductal, Breast / mortality
  • Carcinoma, Ductal, Breast / surgery*
  • Carcinoma, Intraductal, Noninfiltrating / complications
  • Carcinoma, Intraductal, Noninfiltrating / mortality
  • Carcinoma, Intraductal, Noninfiltrating / surgery*
  • Carcinoma, Lobular / complications
  • Carcinoma, Lobular / mortality
  • Carcinoma, Lobular / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Hypertrophy / complications
  • Hypertrophy / surgery*
  • Mammaplasty / methods*
  • Mastectomy, Segmental*
  • Middle Aged
  • Retrospective Studies
  • Survival Analysis
  • Treatment Outcome

Supplementary concepts

  • Gigantomastia