The Metastatic Spine Disease Multidisciplinary Working Group Algorithms

Adam N Wallace; Clifford G Robinson; Jeffrey Meyer; Nam D Tran; Afshin Gangi; Matthew R Callstrom; Samuel T Chao; Brian A Van Tine; Jonathan M Morris; Brian M Bruel; Jeremiah Long; Robert D Timmerman; Jacob M Buchowski; Jack W Jennings

doi:10.1634/theoncologist.2015-0085

The Metastatic Spine Disease Multidisciplinary Working Group Algorithms

Oncologist. 2015 Oct;20(10):1205-15. doi: 10.1634/theoncologist.2015-0085. Epub 2015 Sep 9.

Affiliations

¹ Mallinckrodt Institute of Radiology, Department of Radiation Oncology, Department of Internal Medicine, and Department of Orthopaedic Surgery, Washington University School of Medicine, Saint Louis, Missouri, USA; Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Neurooncology Program, H. Lee Moffitt Cancer Center and Research Institute, Department of Neurosurgery, and Department of Orthopedics, University of South Florida College of Medicine, Tampa, Florida, USA; Department of Interventional Radiology, University of Strasbourg School of Medicine, Strasbourg, France; Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA; Department of Anesthesiology and Pain Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Department of Radiation Oncology, Cleveland Clinic, Cleveland, Ohio, USA wallacea@mir.wustl.edu.
² Mallinckrodt Institute of Radiology, Department of Radiation Oncology, Department of Internal Medicine, and Department of Orthopaedic Surgery, Washington University School of Medicine, Saint Louis, Missouri, USA; Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Neurooncology Program, H. Lee Moffitt Cancer Center and Research Institute, Department of Neurosurgery, and Department of Orthopedics, University of South Florida College of Medicine, Tampa, Florida, USA; Department of Interventional Radiology, University of Strasbourg School of Medicine, Strasbourg, France; Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA; Department of Anesthesiology and Pain Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Department of Radiation Oncology, Cleveland Clinic, Cleveland, Ohio, USA.

Abstract

The Metastatic Spine Disease Multidisciplinary Working Group consists of medical and radiation oncologists, surgeons, and interventional radiologists from multiple comprehensive cancer centers who have developed evidence- and expert opinion-based algorithms for managing metastatic spine disease. The purpose of these algorithms is to facilitate interdisciplinary referrals by providing physicians with straightforward recommendations regarding the use of available treatment options, including emerging modalities such as stereotactic body radiation therapy and percutaneous tumor ablation. This consensus document details the evidence supporting the Working Group algorithms and includes illustrative cases to demonstrate how the algorithms may be applied.

Keywords: Ablation techniques; Kyphoplasty; Metastatic; Radiotherapy; Spine; Vertebroplasty.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Combined Modality Therapy
Fractures, Compression / etiology
Fractures, Compression / therapy
Humans
Joint Instability / etiology
Joint Instability / therapy
Practice Guidelines as Topic
Spinal Cord Compression / etiology
Spinal Cord Compression / therapy
Spinal Fractures / etiology
Spinal Fractures / therapy
Spinal Neoplasms / complications
Spinal Neoplasms / secondary
Spinal Neoplasms / therapy*