The osmotic second virial coefficient for protein self-interaction: Use and misuse to describe thermodynamic nonideality

Anal Biochem. 2015 Dec 1:490:55-65. doi: 10.1016/j.ab.2015.08.020. Epub 2015 Sep 3.

Authors

Peter R Wills¹, David J Scott², Donald J Winzor³

Affiliations

¹ Department of Physics, University of Auckland, PB 92019, Auckland 1142, New Zealand. Electronic address: p.wills@auckland.ac.nz.
² Centre for Macromolecular Hydrodynamics, School of Biosciences, University of Nottingham, Sutton Bonington, LE12 5RD, UK.
³ School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland 4072, Australia.

PMID: 26344712
DOI: 10.1016/j.ab.2015.08.020

No abstract available

Publication types

Review

MeSH terms

Algorithms
Animals
Chemical Phenomena
Dimerization
Humans
Models, Molecular*
Osmotic Pressure
Protein Aggregates
Protein Conformation
Protein Interaction Domains and Motifs
Proteins / analysis
Proteins / chemistry*
Solubility
Stress, Mechanical
Thermodynamics

Substances

Protein Aggregates
Proteins

Grants and funding

BB/F011156/1/BB_/Biotechnology and Biological Sciences Research Council/United Kingdom