Reversible morphology transitions of supramolecular polymer self-assemblies for switch-controlled drug release

Chem Commun (Camb). 2015 Oct 28;51(84):15366-9. doi: 10.1039/c5cc05579b.

Abstract

A novel method for switch-controlled drug release was developed through the reversible morphology transitions of supramolecular branched copolymer self-assemblies. The reversible transitions from vesicles to nanoparticles were successfully achieved by alternating UV and visible light irradiation to obtain morphology-controlled drug release in a switch mode.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Doxycycline / analysis*
  • Doxycycline / chemistry*
  • Drug Liberation*
  • Light
  • Particle Size
  • Polymers / chemical synthesis*
  • Polymers / chemistry*
  • Surface Properties
  • Ultraviolet Rays

Substances

  • Polymers
  • Doxycycline