Skincare products with multiple beneficial functions are currently of great interest to most cosmeceutical consumers in the world, which provides a strong driving force for the search of new bio-active ingredients. Along with the development of cosmeceuticals, seeking the efficient delivery systems to convey these active substances to the human skin has also gained increasing attention in the field of research and development. In order to elevate the delivery efficacy of cosmetics/drugs, colloidal carriers such as vesicles, nano/micro-emulsions, and nano/micro-particles have been widely developed. This review focuses on the recent investigations of lipid- and surfactant-based vesicles for cosmeceutical applications. Categories, preparation methods, physicochemical characteristics, and safety and efficacy evaluations of lipid- and surfactant-based vesicles capable of delivering cosmeceuticals are discussed in this review.