High prevalence of seasonal affective disorder among persons with severe visual impairment

Br J Psychiatry. 2016 Jan;208(1):56-61. doi: 10.1192/bjp.bp.114.162354. Epub 2015 Sep 3.

Abstract

Background: Light severely affects the occurrence of seasonal affective disorder (SAD).

Aims: To compare the prevalence of SAD in persons with severe visual impairment and persons with full sight, and in persons with severe visual impairment with or without light perception.

Method: This cross-sectional study assessed the Global Seasonality Score (GSS) and the prevalence of SAD among 2781 persons with visual impairment and 4099 persons with full sight using the Seasonal Pattern Assessment Questionnaire (SPAQ).

Results: Respondents with visual impairment had significantly higher GSS and prevalence of SAD compared with full sight controls, P<0.001. Light perception respondents were more vulnerable to seasonal change than both full sight and no light perception respondents.

Conclusions: The study showed a highly significant association between visual impairment and SPAQ-defined SAD parameters, supporting the hypothesis that decreased retinal light input plays a role in the pathogenesis of SAD.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cross-Sectional Studies
  • Denmark / epidemiology
  • Female
  • Humans
  • Light*
  • Linear Models
  • Male
  • Middle Aged
  • Seasonal Affective Disorder / epidemiology*
  • Surveys and Questionnaires
  • Vision Disorders / complications*
  • Visual Perception*