Xanthones from the herb of Swertia elata and their anti-TMV activity

Nat Prod Res. 2016 Aug;30(16):1810-5. doi: 10.1080/14786419.2015.1081198. Epub 2015 Sep 2.

Abstract

Two new xanthones (1-2), together with four known ones (3-6), were isolated from whole herb of Swertia elata. Their structures were elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Their anti-tobacco mosaic virus (anti-TMV) activity test revealed that 1-6 showed weak anti-TMV activities with inhibition rate in the range of 15.2-28.8% at the concentration of 20 μM.

Keywords: Swertia elata; anti-TMV activity; xanthones.

MeSH terms

  • Antiviral Agents / chemistry
  • Antiviral Agents / isolation & purification
  • Antiviral Agents / pharmacology
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Swertia / chemistry*
  • Tobacco Mosaic Virus / drug effects*
  • Xanthones / chemistry
  • Xanthones / isolation & purification*
  • Xanthones / pharmacology

Substances

  • Antiviral Agents
  • Xanthones