Stent Repair for Complex Coarctation of Aorta

JACC Cardiovasc Interv. 2015 Aug 24;8(10):1368-1379. doi: 10.1016/j.jcin.2015.05.018.

Abstract

Objectives: This study sought to determine whether several anatomic or evolving characteristics of the coarctation may create challenging conditions for treatment.

Background: Stent repair of coarctation of aorta is an alternative to surgical correction.

Methods: We analyzed our 21-year experience in the percutaneous treatment of complex coarctation of aorta. Adverse conditions for treatment were as follow: 1) complete interruption of the aortic arch (n = 11); 2) associated aneurysm (n = 18); 3) complex stenosis (n = 30); and 4) the need for re-expansion and/or restenting (n = 21). Twenty patients (33%) belonged to more than 1 group. Ten interruptions were type A and 1 was type B. The mean length of the interrupted aorta was 9 ± 11 mm. The associated aneurysms were native in 8 patients and after previous intervention in 10 patients. Aneurysm shapes were fusiform in 8 patients and saccular in 10. The following characteristics defined complex stenosis as long diffuse stenosis, very tortuous coarctation, or stenosis involving a main branch or an unusual location. Patients previously stented at an early age, required re-expansion and/or restenting after reaching 16 ± 5 years of age.

Results: Two patients had died by 1-month follow-up. The remaining 58 patients did well and were followed-up for a mean period of 10 ± 6 years. Late adverse events occurred in 3 patients (5%). All remaining patients are symptom-free, with normal baseline blood pressure. Imaging techniques revealed good patency at follow-up without associated aneurysm or restenosis. The actuarial survival free probability of all complex patients at 15 years was 92%.

Conclusions: Stent repair of complex coarctation of aorta is feasible and safe. Initial results are maintained at later follow-up.

Keywords: aortic aneurysm; complex coarctation of aorta; interrupted aortic arch; stent re-expansion; stent repair.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aortic Aneurysm / diagnosis
  • Aortic Aneurysm / mortality
  • Aortic Aneurysm / physiopathology
  • Aortic Aneurysm / therapy*
  • Aortic Coarctation / diagnosis
  • Aortic Coarctation / mortality
  • Aortic Coarctation / physiopathology
  • Aortic Coarctation / therapy*
  • Aortography / methods
  • Arterial Occlusive Diseases / diagnosis
  • Arterial Occlusive Diseases / mortality
  • Arterial Occlusive Diseases / physiopathology
  • Arterial Occlusive Diseases / therapy*
  • Child
  • Child, Preschool
  • Constriction, Pathologic
  • Endovascular Procedures / adverse effects
  • Endovascular Procedures / instrumentation*
  • Endovascular Procedures / mortality
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prosthesis Design
  • Retrospective Studies
  • Spain
  • Stents*
  • Time Factors
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Vascular Patency
  • Young Adult