Performance of Xpert MTB/RIF Assay in Diagnosis of Pleural Tuberculosis by Use of Pleural Fluid Samples

J Clin Microbiol. 2015 Nov;53(11):3636-8. doi: 10.1128/JCM.02182-15. Epub 2015 Aug 26.

Abstract

Prospectively, 162 pleural fluid samples from patients with probable tuberculous pleural effusion were tested by the Xpert MTB/RIF assay and the Bactec MGIT-960 culture system. Of these, 43 (26.5%) were positive in the MGIT-960 culture, and 23 (14.2%), in the Xpert MTB/RIF assay. The sensitivity and specificity of the Xpert MTB/RIF compared with the MGIT-960 culture were 54.8% and 100%, respectively.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Female
  • Humans
  • Male
  • Molecular Diagnostic Techniques / instrumentation
  • Molecular Diagnostic Techniques / methods*
  • Mycobacterium tuberculosis / genetics*
  • Pleura / microbiology*
  • Pleura / pathology
  • Pleural Effusion / microbiology*
  • Prospective Studies
  • Sensitivity and Specificity
  • Tuberculosis, Pleural / diagnosis*
  • Tuberculosis, Pleural / microbiology