H2 oxidation versus organic substrate oxidation in non-heme iron mediated reactions with H2O2

Chem Commun (Camb). 2015 Oct 18;51(81):14992-5. doi: 10.1039/c5cc06402c.

Abstract

Herein we show that species generated upon reaction of α-[Fe(CF3SO3)2(BPMCN)] (BPMCN = N,N'-bis(2-pyridylmethyl)-trans-1,2-diaminocyclohexane) with H2O2 (putatively [Fe(V)(O)(OH)(BPMCN)]) is able to efficiently oxidize H2 to H2O even in the presence of organic substrates, while species formed in the presence of acetic acid (putatively [Fe(V)(O)(OAc)(BPMCN)]) prefer organic substrate oxidation over H2 activation. Mechanistic implications have been analysed with the aid of computational methods.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Heme
  • Hydrogen / chemistry*
  • Hydrogen Peroxide / chemistry*
  • Iron Compounds / chemistry*
  • Molecular Conformation
  • Oxidation-Reduction
  • Water / chemistry*

Substances

  • Iron Compounds
  • Water
  • Heme
  • Hydrogen
  • Hydrogen Peroxide