Gamma regularization based reconstruction for low dose CT

Phys Med Biol. 2015 Sep 7;60(17):6901-21. doi: 10.1088/0031-9155/60/17/6901. Epub 2015 Aug 25.

Abstract

Reducing the radiation in computerized tomography is today a major concern in radiology. Low dose computerized tomography (LDCT) offers a sound way to deal with this problem. However, more severe noise in the reconstructed CT images is observed under low dose scan protocols (e.g. lowered tube current or voltage values). In this paper we propose a Gamma regularization based algorithm for LDCT image reconstruction. This solution is flexible and provides a good balance between the regularizations based on l0-norm and l1-norm. We evaluate the proposed approach using the projection data from simulated phantoms and scanned Catphan phantoms. Qualitative and quantitative results show that the Gamma regularization based reconstruction can perform better in both edge-preserving and noise suppression when compared with other norms.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Dose-Response Relationship, Radiation
  • Gamma Rays*
  • Humans
  • Phantoms, Imaging*
  • Radiation Protection / standards*
  • Radiographic Image Interpretation, Computer-Assisted / methods*
  • Radiographic Image Interpretation, Computer-Assisted / standards
  • Tomography, X-Ray Computed / methods*