Micro-thermography in millimeter-scale animals by using orally-dosed fluorescent nanoparticle thermosensors

Analyst. 2015 Nov 21;140(22):7534-9. doi: 10.1039/c5an01287b.

Abstract

We propose an instant micro-thermography method using a fluorescent-nanoparticle thermosensor capable of reporting temperature as the fluorescence intensity ratio of the temperature-sensitive dye to the reference. We demonstrate "temperature mapping" inside a fruit fly larva that was orally dosed with nanoparticle thermosensors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Body Temperature*
  • Drosophila / physiology*
  • Fluorescent Dyes / analysis*
  • Larva / physiology
  • Nanoparticles / analysis*
  • Optical Imaging / methods
  • Thermography / methods*

Substances

  • Fluorescent Dyes