The Role of Bone Morphogenetic Proteins 2, 7, and 14 in Approaches for Intervertebral Disk Restoration

World Neurosurg. 2015 Oct;84(4):871-3. doi: 10.1016/j.wneu.2015.08.011. Epub 2015 Aug 20.

Authors

Evgenii Belykh¹, Morgan Giers², Liudmila Bardonova³, Nicholas Theodore², Mark Preul², Vadim Byvaltsev⁴

Affiliations

¹ Irkutsk Scientific Center of Surgery and Traumatology, Irkutsk, Russia; Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.
² Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.
³ Irkutsk Scientific Center of Surgery and Traumatology, Irkutsk, Russia; Irkutsk State Medical University, Irkutsk, Russia.
⁴ Irkutsk Scientific Center of Surgery and Traumatology, Irkutsk, Russia; Irkutsk State Medical University, Irkutsk, Russia; Railway Clinical Hospital, Irkutsk-Passazhirskiy Station of Russian Railways Ltd., Irkutsk, Russia.

PMID: 26299263
DOI: 10.1016/j.wneu.2015.08.011

No abstract available

Publication types

News
Research Support, Non-U.S. Gov't

MeSH terms

Bone Morphogenetic Protein 2 / genetics
Bone Morphogenetic Protein 2 / physiology
Bone Morphogenetic Protein 2 / therapeutic use*
Bone Morphogenetic Protein 7 / genetics
Bone Morphogenetic Protein 7 / physiology
Bone Morphogenetic Protein 7 / therapeutic use*
Bone Transplantation
Drug Delivery Systems
Growth Differentiation Factor 5 / genetics
Growth Differentiation Factor 5 / physiology
Growth Differentiation Factor 5 / therapeutic use*
Humans
Intervertebral Disc Degeneration / genetics
Intervertebral Disc Degeneration / surgery
Intervertebral Disc Degeneration / therapy*
Recombinant Proteins / therapeutic use*
Spinal Fusion / methods

Substances

BMP2 protein, human
BMP7 protein, human
Bone Morphogenetic Protein 2
Bone Morphogenetic Protein 7
GDF5 protein, human
Growth Differentiation Factor 5
Recombinant Proteins