[Clinical and immunological profile of HIV-infected patients at the initiation of antiretroviral therapy in Douala]

Bull Soc Pathol Exot. 2015 Oct;108(4):255-61. doi: 10.1007/s13149-015-0444-3. Epub 2015 Aug 22.
[Article in French]

Abstract

The aim of this study was to describe the clinical and immunological profile of patients infected with HIV after initiation of antiretroviral therapy. Sociodemographic characteristics, clinical and immunological patients were recorded. Chi square test and Mann-Whitney were used to compare variables. The multivariate regression model identified risk factors. So that, 936 (56.2%) patients were in stages III and IV of the WHO and 65.2% at an advanced stage of the disease. Factors associated with initiation at an advanced stage, were male sex (p = 0.007) and time to diagnosis (p = 0.005). In 2/3 cases, treatment is started at an advanced stage of disease. It is therefore important to intensify awareness campaigns for early detection and encourage patients to ensure regular medical follow-up screening.

Keywords: Bioclinical profile; Cameroon; District Hospital of Bonassama; District Hospital of Nylon; General hospital of Douala; Initiation of antiretroviral therapy; PLHIV; Sub-Saharan Africa.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Anti-HIV Agents / therapeutic use
  • Anti-Retroviral Agents / therapeutic use*
  • CD4 Lymphocyte Count
  • Cameroon / epidemiology
  • Cross-Sectional Studies
  • Female
  • HIV Infections / drug therapy*
  • HIV Infections / epidemiology*
  • HIV Infections / immunology*
  • HIV-1
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Factors

Substances

  • Anti-HIV Agents
  • Anti-Retroviral Agents