Ligand-induced STAT3 signaling increases at relapse and is associated with outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group

Haematologica. 2015 Dec;100(12):e496-500. doi: 10.3324/haematol.2015.131508. Epub 2015 Aug 20.
No abstract available

Keywords: STAT3; acute myeloid leukemia; ligand stimulation; pediatric; relapse.

Publication types

  • Letter
  • Multicenter Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Leukemia, Myeloid, Acute / genetics
  • Leukemia, Myeloid, Acute / metabolism*
  • Leukemia, Myeloid, Acute / mortality
  • Leukemia, Myeloid, Acute / pathology
  • Leukemia, Myeloid, Acute / therapy
  • Male
  • Recurrence
  • STAT3 Transcription Factor / metabolism*
  • Signal Transduction*

Substances

  • STAT3 Transcription Factor
  • STAT3 protein, human