Multimodality Brain Tumor Imaging: MR Imaging, PET, and PET/MR Imaging

J Nucl Med. 2015 Oct;56(10):1554-61. doi: 10.2967/jnumed.113.131516. Epub 2015 Aug 20.

Abstract

Standard MR imaging and CT are routinely used for anatomic diagnosis in brain tumors. Pretherapy planning and posttreatment response assessments rely heavily on gadolinium-enhanced MR imaging. Advanced MR imaging techniques and PET imaging offer physiologic, metabolic, or functional information about tumor biology that goes beyond the diagnostic yield of standard anatomic imaging. With the advent of combined PET/MR imaging scanners, we are entering an era wherein the relationships among different elements of tumor metabolism can be simultaneously explored through multimodality MR imaging and PET imaging. The purpose of this review is to provide a practical and clinically relevant overview of current anatomic and physiologic imaging of brain tumors as a foundation for further investigations, with a primary focus on MR imaging and PET techniques that have demonstrated utility in the current care of brain tumor patients.

Keywords: brain tumor; magnetic resonance imaging; positron emission tomography.

Publication types

  • Review

MeSH terms

  • Brain Neoplasms / diagnostic imaging*
  • Brain Neoplasms / pathology*
  • Brain Neoplasms / therapy
  • Diffusion Magnetic Resonance Imaging
  • Humans
  • Magnetic Resonance Imaging
  • Magnetic Resonance Spectroscopy
  • Multimodal Imaging / methods*
  • Positron-Emission Tomography
  • Radiopharmaceuticals
  • Treatment Outcome

Substances

  • Radiopharmaceuticals